David Q-H Wang Selected Research

Cholic Acid

7/2006	Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice.
8/2004	Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis.
3/2004	Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation.
11/2002	Lith genes control mucin accumulation, cholesterol crystallization, and gallstone formation in A/J and AKR/J inbred mice.
11/2002	Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice.
11/2002	Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice.
7/2002	Susceptibility to murine cholesterol gallstone formation is not affected by partial disruption of the HDL receptor SR-BI.

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David Q-H Wang Research Topics

Disease

59	Gallstones (Gallstone) 01/2022 - 01/2002
34	Cholelithiasis 11/2022 - 02/2002
10	Insulin Resistance 05/2020 - 11/2010
8	Non-alcoholic Fatty Liver Disease 07/2021 - 01/2012
7	Atherosclerosis 11/2021 - 09/2007
7	Body Weight (Weight, Body) 01/2021 - 02/2002
7	Metabolic Diseases (Metabolic Disease) 01/2020 - 06/2008
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2020 - 01/2018
6	Obesity 11/2020 - 05/2013
5	Fistula 01/2022 - 05/2003
5	Liver Diseases (Liver Disease) 07/2021 - 01/2012
4	Fatty Liver 07/2021 - 05/2013
4	Fibrosis (Cirrhosis) 07/2021 - 11/2017
4	Inflammation (Inflammations) 01/2021 - 04/2009
3	Cholestasis 11/2022 - 05/2007
3	Neoplasms (Cancer) 02/2019 - 11/2017
3	AIDS-Related Complex (ARC) 02/2019 - 02/2010
3	Digestive System Diseases 01/2018 - 01/2012
3	Hypercholesterolemia 01/2012 - 08/2005
2	Pancreatitis 01/2022 - 12/2018
2	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021 - 01/2021
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2020 - 01/2020
2	Dyslipidemias (Dyslipidemia) 12/2020 - 01/2019
2	Celiac Disease (Celiac Sprue) 11/2020 - 01/2019
2	Sitosterolemia 01/2020 - 01/2007
2	Weight Loss (Weight Reduction) 12/2018 - 08/2014
2	Coronary Disease (Coronary Heart Disease) 11/2017 - 11/2017
1	Hepatocellular Carcinoma (Hepatoma) 07/2021
1	Alcoholic Fatty Liver 07/2021
1	progressive familial intrahepatic 1 Cholestasis 01/2021
1	Hypertension (High Blood Pressure) 05/2020
1	Hypertriglyceridemia 05/2020
1	Hyperglycemia 05/2020
1	Abdominal Obesity 05/2020
1	Dyspepsia (Indigestion) 03/2019

Drug/Important Bio-Agent (IBA)

65	CholesterolIBA 11/2022 - 01/2002
17	LipidsIBA 01/2022 - 11/2002
17	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 11/2002
10	Ezetimibe (Zetia)FDA Link 01/2017 - 08/2005
9	Estrogens (Estrogen)FDA Link 12/2020 - 07/2004
7	MucinsIBA 02/2010 - 02/2002
7	Cholic AcidIBA 07/2006 - 07/2002
6	Phospholipids (Phosphatides)FDA LinkGeneric 11/2022 - 01/2004
6	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2012
6	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 12/2018 - 11/2002
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2015 - 08/2005
5	Estrogen ReceptorsIBA 12/2020 - 09/2015
4	Triglycerides (Triacylglycerol)IBA 01/2022 - 10/2013
4	Lipoproteins (Lipoprotein)IBA 01/2021 - 09/2007
4	Oral ContraceptivesIBA 11/2020 - 07/2004
4	Therapeutic UsesIBA 11/2017 - 02/2015
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2007
3	SterolsIBA 01/2020 - 01/2007
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2019 - 01/2012
3	Cholecystokinin (Pancreozymin)IBA 01/2019 - 03/2015
3	BilirubinIBA 01/2016 - 05/2011
2	Hormones (Hormone)IBA 11/2021 - 02/2019
2	Pharmaceutical PreparationsIBA 07/2021 - 01/2012
2	IsotopesIBA 07/2021 - 05/2003
2	EnzymesIBA 01/2021 - 05/2011
2	Messenger RNA (mRNA)IBA 01/2021 - 08/2009
2	Apolipoproteins E (ApoE)IBA 01/2021 - 08/2009
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2020 - 09/2015
2	Conjugated (USP) Estrogens (Premarin)FDA Link 11/2020 - 07/2004
2	Phytosterols (Plant Sterols)IBA 01/2020 - 01/2007
2	Appetite Depressants (Anorectics)IBA 01/2018 - 07/2010
2	Adenosine Triphosphate (ATP)IBA 01/2016 - 01/2007
2	ginsenoside Rb1IBA 09/2015 - 05/2013
2	AMP-Activated Protein KinasesIBA 09/2015 - 05/2013
2	MicellesIBA 12/2014 - 06/2008
2	AntioxidantsIBA 08/2014 - 05/2007
2	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 01/2014 - 01/2007
2	ChylomicronsIBA 01/2012 - 03/2005
2	ApolipoproteinsIBA 08/2009 - 10/2005
2	Dietary CholesterolIBA 01/2008 - 10/2005
2	high density lipoprotein receptorsIBA 07/2002 - 01/2002
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 11/2021
1	Methionine (L-Methionine)FDA Link 07/2021
1	octanoic acid (caprylic acid)IBA 07/2021
1	AcidsIBA 07/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2021
1	Nonesterified Fatty Acids (NEFA)IBA 05/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Phosphatidylcholines (Phosphatidylcholine)IBA 01/2021
1	Soybean Proteins (Soy Protein)IBA 12/2020
1	Cholecystokinin A ReceptorIBA 11/2020
1	Sincalide FDA Link 11/2020
1	HDL CholesterolIBA 05/2020
1	LigandsIBA 01/2020
1	GTP-Binding Proteins (G-Protein)IBA 01/2020
1	Lactulose (Duphalac)FDA LinkGeneric 03/2019
1	HydrogenIBA 03/2019

Therapy/Procedure

16	Therapeutics 01/2021 - 08/2005
8	Cholecystectomy 11/2022 - 08/2014
3	Total Parenteral Nutrition 11/2020 - 12/2018
3	Laparoscopic Cholecystectomy 01/2017 - 01/2009
2	Bariatric Surgery 11/2017 - 08/2014
1	Sphincterotomy 01/2022
1	Injections 01/2021
1	Liver Transplantation 01/2021